Cincinnati vs Iowa State Prediction, Picks & Odds (Week 11)
Sun, Nov 15, 12:00 AM ET
About this game
This season, Cincinnati is 4-0 with 162 points for and 82 against; Iowa State is 2-2 with 123 points for and 64 against.
Cincinnati is 4-1 in its last 5, averaging 35.0 scored and 23.4 allowed; most recently beating Kansas State 31-26 on September 26, 2026. Iowa State is 3-2 in its last 5, averaging 28.6 scored and 15.4 allowed; most recently losing to Utah 17-31 on September 26, 2026.
These teams have met once in our results history, on October 4, 2025: Iowa State 30, Cincinnati 38.
Injury report: Cincinnati lists 2 (DaMari Witherspoon, Injured; CD McFee, Injured); Iowa State lists 6 (Salahadin Allah, Injured; Evan Boyd, Injured; Carter Pabst, Injured; more below).
Injuries
Cincinnati
- DaMari Witherspoon: Injured, Undisclosed
- CD McFee: Injured, Undisclosed
Iowa State
- Salahadin Allah: Injured, Lower Leg
- Evan Boyd: Injured, Undisclosed
- Carter Pabst: Injured, Undisclosed
- Tristan Exline: Injured, Undisclosed
- Sullivan Schlimgen: Injured, Lower Leg
- Micah Harper: Injured, Undisclosed
Recent form
Cincinnati
- September 26, 2026: W 31-26 vs Kansas State
- September 19, 2026: W 35-31 vs Miami (OH)
- September 12, 2026: W 62-10 vs Western Carolina
- September 5, 2026: W 34-15 vs Boston College
- January 2, 2026: L 13-35 vs Navy
Iowa State
- September 26, 2026: L 17-31 vs Utah
- September 19, 2026: W 55-7 vs Bowling Green
- September 12, 2026: L 13-16 at Iowa
- September 5, 2026: W 38-10 vs Southeast Missouri State
- November 29, 2025: W 20-13 at Oklahoma State
Head to head
- October 4, 2025: Iowa State 30, Cincinnati 38