Syracuse vs Virginia Prediction, Picks & Odds (Week 6)

Sat, Oct 10, 7:30 PM ET

Market favorite

Virginia moneyline -357, published Oct 4, 2026, 10:30 AM ET.

About this pick

Virginia is the market favorite on the moneyline at -357 when the pick was published on Oct 4. Until our ratings model is live, each pick is the market favorite, and that price implies a 78% chance of Virginia winning.

This season, Syracuse is 1-2 with 97 points for and 51 against; Virginia is 3-1 with 162 points for and 52 against.

Syracuse is 1-4 in its last 5, averaging 23.2 scored and 31.0 allowed; most recently losing to Pittsburgh 13-27 on September 17, 2026. Virginia is 4-1 in its last 5, averaging 35.0 scored and 11.8 allowed; most recently beating Delaware 42-3 on September 26, 2026.

Injury report: Syracuse lists 8 (Steve Angeli, Injured; Ju'Juan Johnson, Injured; Nate Edwards, Injured; more below); Virginia lists 7 (Solomon Beebe, Injured; Jack Stevens, Injured; Dillon NewtonShort, Injured; more below).

Injuries

Syracuse

  • Steve Angeli: Injured, Undisclosed
  • Ju'Juan Johnson: Injured, Hand
  • Nate Edwards: Injured, Undisclosed
  • Terrell Wilfong: Injured, Collarbone
  • Wyatt Bowman: Injured, Undisclosed
  • Elijah Crawford: Injured, Collarbone
  • Jai Eugene Jr.: Injured, Undisclosed
  • Chase Geter: Injured, Hand

Virginia

  • Solomon Beebe: Injured, Suspension
  • Jack Stevens: Injured, Undisclosed
  • Dillon NewtonShort: Injured, Hamstring
  • Triston Ward: Injured, Undisclosed
  • Dallas Brannon: Injured, Suspension
  • Lukas Sanker: Injured, Hamstring
  • Jaylen Jones: Injured, Undisclosed

Recent form

Syracuse

  • September 17, 2026: L 13-27 at Pittsburgh
  • September 12, 2026: L 18-21 vs California
  • September 5, 2026: W 66-3 vs New Hampshire
  • November 29, 2025: L 12-34 vs Boston College
  • November 22, 2025: L 7-70 at Notre Dame

Virginia

  • September 26, 2026: W 42-3 vs Delaware
  • September 19, 2026: L 27-38 vs West Virginia
  • September 11, 2026: W 59-3 vs Norfolk State
  • August 29, 2026: W 34-8 vs NC State
  • December 27, 2025: W 13-7 at Missouri

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