South Florida vs UTSA Prediction, Picks & Odds (Week 6)

Thu, Oct 8, 7:30 PM ET

Our pick

UTSA moneyline -278, published Oct 4, 2026, 8:44 AM ET.

Why we pick UTSA

We pick UTSA on the moneyline at -278 when we published it on Oct 4. We back the side the odds favor, and that price implies a 74% chance of UTSA winning.

This season, South Florida is 4-0 with 120 points for and 56 against; UTSA is 3-1 with 141 points for and 117 against.

South Florida is 4-1 in its last 5, averaging 26.0 scored and 16.0 allowed; most recently beating Bowling Green 14-6 on September 26, 2026. UTSA is 4-1 in its last 5, averaging 39.6 scored and 27.4 allowed; most recently beating Colorado State 59-45 on September 26, 2026.

These teams have met once in our results history, on November 6, 2025: UTSA 23, South Florida 55.

Injury report: South Florida lists 9 (Jaden Alexis, Injured; Arhmad Branch, Injured; Gabe Legrand, Injured; more below); UTSA lists 4 (Bryson Donnell, Injured; Mykha Green, Injured; Brandon Tucker, Injured; more below).

Injuries

South Florida

  • Jaden Alexis: Injured, Undisclosed
  • Arhmad Branch: Injured, Undisclosed
  • Gabe Legrand: Injured, Undisclosed
  • Dmari Roberts: Injured, Undisclosed
  • Cameron Seldon: Injured, Undisclosed
  • Michael Williams II: Injured, Undisclosed
  • Asani Redwood: Injured, Undisclosed
  • Grayson Howard: Injured, Undisclosed
  • Jabari Smith: Injured, Undisclosed

UTSA

  • Bryson Donnell: Injured, Undisclosed
  • Mykha Green: Injured, Undisclosed
  • Brandon Tucker: Injured, Undisclosed
  • Elijah Newell: Injured, Undisclosed

Recent form

South Florida

  • September 26, 2026: W 14-6 at Bowling Green
  • September 19, 2026: W 59-17 vs Delaware State
  • September 12, 2026: W 28-24 at Army
  • September 5, 2026: W 19-9 vs Florida International
  • December 17, 2025: L 10-24 vs Old Dominion

UTSA

  • September 26, 2026: W 59-45 vs Colorado State
  • September 19, 2026: L 6-30 at Texas
  • September 12, 2026: W 31-26 at Texas State
  • September 5, 2026: W 45-16 vs UT Rio Grande Valley
  • December 26, 2025: W 57-20 vs Florida International

Head to head

  • November 6, 2025: UTSA 23, South Florida 55

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