South Florida vs East Carolina Prediction, Picks & Odds (Week 10)
Fri, Nov 6, 7:30 PM ET
Why we pick this side
This season, South Florida is 4-0 with 120 points for and 56 against; East Carolina is 2-2 with 96 points for and 101 against.
South Florida is 4-1 in its last 5, averaging 26.0 scored and 16.0 allowed; most recently beating Bowling Green 14-6 on September 26, 2026. East Carolina is 3-2 in its last 5, averaging 23.8 scored and 23.6 allowed; most recently beating North Carolina Central 42-9 on September 26, 2026.
Injury report: South Florida lists 9 (Jaden Alexis, Injured; Arhmad Branch, Injured; Gabe Legrand, Injured; more below); East Carolina lists 7 (Ashton Gray, Injured; Meliq Mcgowan, Injured; Brock Spalding, Injured; more below).
Injuries
South Florida
- Jaden Alexis: Injured, Undisclosed
- Arhmad Branch: Injured, Undisclosed
- Gabe Legrand: Injured, Undisclosed
- Dmari Roberts: Injured, Undisclosed
- Cameron Seldon: Injured, Undisclosed
- Michael Williams II: Injured, Undisclosed
- Asani Redwood: Injured, Undisclosed
- Grayson Howard: Injured, Undisclosed
- Jabari Smith: Injured, Undisclosed
East Carolina
- Ashton Gray: Injured, Undisclosed
- Meliq Mcgowan: Injured, Undisclosed
- Brock Spalding: Injured, Back
- Crews Law: Injured, Back
- Josh Benton: Injured, Undisclosed
- Zyeir Gamble: Injured, Undisclosed
- Tavius Horne Jr.: Injured, Undisclosed
Recent form
South Florida
- September 26, 2026: W 14-6 at Bowling Green
- September 19, 2026: W 59-17 vs Delaware State
- September 12, 2026: W 28-24 at Army
- September 5, 2026: W 19-9 vs Florida International
- December 17, 2025: L 10-24 vs Old Dominion
East Carolina
- September 26, 2026: W 42-9 vs North Carolina Central
- September 19, 2026: W 20-17 at Old Dominion
- September 12, 2026: L 24-27 vs App State
- September 5, 2026: L 10-48 at Alabama
- December 27, 2025: W 23-17 vs Pittsburgh