South Carolina vs Florida Prediction, Picks & Odds (Week 6)
Sat, Oct 10, 12:45 PM ET
Market favorite
Florida moneyline -769, published Oct 3, 2026, 12:28 PM ET.
About this pick
Florida is the market favorite on the moneyline at -769 when the pick was published on Oct 3. Until our ratings model is live, each pick is the market favorite, and that price implies a 88% chance of Florida winning.
This season, South Carolina is 2-2 with 154 points for and 99 against; Florida is 4-0 with 214 points for and 91 against.
South Carolina is 2-3 in its last 5, averaging 33.6 scored and 25.4 allowed; most recently losing to Alabama 18-49 on September 26, 2026. Florida is 5-0 in its last 5, averaging 50.8 scored and 22.4 allowed; most recently beating Ole Miss 52-28 on September 26, 2026.
Injury report: South Carolina lists 5 (Jayden Gibson, Injured; Jayden Sellers, Injured; Caden Ramsey, Injured; more below); Florida lists 4 (Kelvin Jimenez, Injured; Vernell Brown III, Injured; Kaiden Hall, Injured; more below).
Injuries
South Carolina
- Jayden Gibson: Injured, Lower Body
- Jayden Sellers: Injured, Lower Body
- Caden Ramsey: Injured, Suspension
- Justin Okoronkwo: Injured, Lower Body
- David Bucey: Injured, Lower Body
Florida
- Kelvin Jimenez: Injured, Undisclosed
- Vernell Brown III: Injured, Knee
- Kaiden Hall: Injured, Undisclosed
- Bryce Thornton: Injured, Knee
Recent form
South Carolina
- September 26, 2026: L 18-49 at Alabama
- September 19, 2026: L 34-41 vs Mississippi State
- September 12, 2026: W 45-9 vs Towson
- September 5, 2026: W 57-0 vs Kent State
- November 29, 2025: L 14-28 vs Clemson
Florida
- September 26, 2026: W 52-28 vs Ole Miss
- September 19, 2026: W 44-39 at Auburn
- September 12, 2026: W 52-3 vs Campbell
- September 5, 2026: W 66-21 vs Florida Atlantic
- November 29, 2025: W 40-21 vs Florida State