South Alabama vs Louisiana Prediction, Picks & Odds (Week 10)
Sun, Nov 8, 12:00 AM ET
Why we pick this side
This season, South Alabama is 2-2 with 125 points for and 123 against; Louisiana is 3-1 with 123 points for and 77 against.
South Alabama is 2-3 in its last 5, averaging 30.2 scored and 34.4 allowed; most recently losing to Kentucky 21-45 on September 26, 2026. Louisiana is 3-2 in its last 5, averaging 27.2 scored and 19.4 allowed; most recently beating Charlotte 34-7 on September 26, 2026.
These teams have met once in our results history, on November 1, 2025: Louisiana 31, South Alabama 22.
Injury report: South Alabama lists 8 (Brian Barnes, Injured; Khatori Marion, Injured; Dominic White, Injured; more below); Louisiana list none.
Injuries
South Alabama
- Brian Barnes: Injured, Undisclosed
- Khatori Marion: Injured, Undisclosed
- Dominic White: Injured, Undisclosed
- Maddox Lynch: Injured, Undisclosed
- Andrew Washburn: Injured, Undisclosed
- William Felton IV: Injured, Undisclosed
- Cube Gurley: Injured, Undisclosed
- Cole Blaylock: Injured, Undisclosed
Louisiana
None listed.
Recent form
South Alabama
- September 26, 2026: L 21-45 at Kentucky
- September 19, 2026: W 41-36 vs Ohio
- September 12, 2026: L 24-28 at Tulane
- September 5, 2026: W 39-14 vs SE Louisiana
- November 29, 2025: L 26-49 at Texas State
Louisiana
- September 26, 2026: W 34-7 at Charlotte
- September 19, 2026: W 21-14 vs UAB
- September 12, 2026: L 30-49 at USC
- September 5, 2026: W 38-7 vs Lamar
- December 17, 2025: L 13-20 at Delaware
Head to head
- November 1, 2025: Louisiana 31, South Alabama 22