Ole Miss vs Vanderbilt Prediction, Picks & Odds (Week 6)
Sat, Oct 10, 3:30 PM ET
Market favorite
Ole Miss moneyline -455, published Oct 4, 2026, 10:26 AM ET.
About this pick
Ole Miss is the market favorite on the moneyline at -455 when the pick was published on Oct 4. Until our ratings model is live, each pick is the market favorite, and that price implies a 82% chance of Ole Miss winning.
Line movement: the Ole Miss spread has moved from -10.5 to -10 since Oct 4 (partner sportsbooks).
This season, Ole Miss is 3-1 with 142 points for and 123 against; Vanderbilt is 3-1 with 113 points for and 87 against.
Ole Miss is 3-2 in its last 5, averaging 33.8 scored and 30.8 allowed; most recently losing to Florida 28-52 on September 26, 2026. Vanderbilt is 3-2 in its last 5, averaging 28.0 scored and 24.2 allowed; most recently losing to Auburn 15-21 on September 26, 2026.
Injury report: Ole Miss lists 2 (Kewan Lacy, Injured; Kam Franklin, Injured); Vanderbilt lists 3 (Jared Curtis, Injured; Kahden Smith, Injured; Jaylin Lackey, Injured).
Ole Miss vs Vanderbilt odds
American odds, main line. The best price in each column is in bold.
| Sportsbook | Ole Miss ML | Vanderbilt ML | Ole Miss spread | Vanderbilt spread | Over | Under |
|---|---|---|---|---|---|---|
| BetOnline | — | — | -10 -110 | +10 -110 | O 57.5 -110 | U 57.5 -110 |
Line movement
- Ole Miss spread: -10.5 → -10 since Oct 4 (partner sportsbooks)
Injuries
Ole Miss
- Kewan Lacy: Injured, Shoulder
- Kam Franklin: Injured, Shoulder
Vanderbilt
- Jared Curtis: Injured, Undisclosed
- Kahden Smith: Injured, Undisclosed
- Jaylin Lackey: Injured, Undisclosed
Recent form
Ole Miss
- September 26, 2026: L 28-52 at Florida
- September 19, 2026: W 32-24 vs LSU
- September 12, 2026: W 41-9 vs Charlotte
- September 6, 2026: W 41-38 vs Louisville
- January 8, 2026: L 27-31 vs Miami
Vanderbilt
- September 26, 2026: L 15-21 at Auburn
- September 19, 2026: W 35-31 vs NC State
- September 12, 2026: W 35-26 vs Delaware
- September 5, 2026: W 28-9 vs Austin Peay
- December 31, 2025: L 27-34 vs Iowa
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