Ohio State vs Indiana Prediction, Picks & Odds (Week 7)

Sun, Oct 18, 12:00 AM ET

Why we pick this side

This season, Ohio State is 3-1 with 180 points for and 49 against; Indiana is 4-0 with 174 points for and 39 against.

Ohio State is 3-2 in its last 5, averaging 38.8 scored and 14.6 allowed; most recently beating Illinois 42-19 on September 26, 2026. Indiana is 5-0 in its last 5, averaging 40.2 scored and 12.0 allowed; most recently beating Northwestern 29-23 on September 25, 2026.

These teams have met once in our results history, on December 6, 2025: Indiana 13, Ohio State 10.

Injury report: Ohio State lists 6 (Bo Jackson, Injured; Anthony Rogers, Injured; Amari ValerioHudson, Injured; more below); Indiana lists 4 (Lee Beebe Jr., Injured; Khobie Martin, Injured; Lebron Bond, Injured; more below).

Injuries

Ohio State

  • Bo Jackson: Injured, Shoulder
  • Anthony Rogers: Injured, Undisclosed
  • Amari ValerioHudson: Injured, Undisclosed
  • Jay Timmons: Injured, Shoulder
  • Khmari Bing: Injured, Undisclosed
  • Brenten Jones: Injured, Undisclosed

Indiana

  • Lee Beebe Jr.: Injured, Undisclosed
  • Khobie Martin: Injured, Undisclosed
  • Lebron Bond: Injured, Undisclosed
  • Preston Zachman: Injured, Undisclosed

Recent form

Ohio State

  • September 26, 2026: W 42-19 vs Illinois
  • September 19, 2026: W 59-3 vs Kent State
  • September 12, 2026: L 23-24 at Texas
  • September 5, 2026: W 56-3 vs Ball State
  • December 31, 2025: L 14-24 vs Miami

Indiana

  • September 25, 2026: W 29-23 vs Northwestern
  • September 19, 2026: W 38-0 vs Western Kentucky
  • September 12, 2026: W 55-0 vs Howard
  • September 5, 2026: W 52-16 vs North Texas
  • January 19, 2026: W 27-21 vs Miami

Head to head

  • December 6, 2025: Indiana 13, Ohio State 10

More on this game