North Carolina vs Pittsburgh Prediction, Picks & Odds (Week 6)
Sat, Oct 10, 12:00 PM ET
Our pick
Pittsburgh moneyline -161, published Oct 4, 2026, 8:51 AM ET.
Why we pick Pittsburgh
We pick Pittsburgh on the moneyline at -161 when we published it on Oct 4. We back the side the odds favor, and that price implies a 62% chance of Pittsburgh winning.
This season, North Carolina is 2-1 with 70 points for and 41 against; Pittsburgh is 5-0 with 192 points for and 67 against.
North Carolina is 2-3 in its last 5, averaging 22.8 scored and 23.0 allowed; most recently losing to Clemson 20-28 on September 19, 2026. Pittsburgh is 5-0 in its last 5, averaging 38.4 scored and 13.4 allowed; most recently beating Virginia Tech 35-33 on October 2, 2026.
Injury report: North Carolina lists 7 (Keeyun Chapman, Injured; C.J. Sadler, Injured; Carnell Warren, Injured; more below); Pittsburgh lists 8 (Mason Heintschel, Injured; Rodney Dunbar, Injured; Malik Knight, Injured; more below).
Injuries
North Carolina
- Keeyun Chapman: Injured, Not Injury Related
- C.J. Sadler: Injured, Undisclosed
- Carnell Warren: Injured, Undisclosed
- Jaxxon Warren: Injured, Undisclosed
- Jordan Washington: Injured, Undisclosed
- Tarvorise Brown: Injured, Undisclosed
- Reggie Love II: Injured, Undisclosed
Pittsburgh
- Mason Heintschel: Injured, Knee
- Rodney Dunbar: Injured, Undisclosed
- Malik Knight: Injured, Undisclosed
- Max Hunt: Injured, Undisclosed
- Elijah Lagg: Injured, Undisclosed
- DeMarco Ward: Injured, Undisclosed
- Raion Strader: Injured, Knee
- Cole Woodson: Injured, Undisclosed
Recent form
North Carolina
- September 19, 2026: L 20-28 at Clemson
- September 12, 2026: W 35-3 vs East Tennessee State
- August 29, 2026: W 15-10 at TCU
- November 29, 2025: L 19-42 at NC State
- November 22, 2025: L 25-32 vs Duke
Pittsburgh
- October 2, 2026: W 35-33 at Virginia Tech
- September 26, 2026: W 59-0 vs Bucknell
- September 17, 2026: W 27-13 vs Syracuse
- September 12, 2026: W 12-7 vs UCF
- September 5, 2026: W 59-14 vs Miami (OH)