Michigan State vs Michigan Prediction, Picks & Odds (Week 10)
Sun, Nov 8, 12:00 AM ET
About this game
This season, Michigan State is 2-2 with 88 points for and 85 against; Michigan is 3-1 with 101 points for and 59 against.
Michigan State is 3-2 in its last 5, averaging 25.2 scored and 22.6 allowed; most recently losing to Nebraska 13-31 on September 26, 2026. Michigan is 3-2 in its last 5, averaging 25.6 scored and 20.0 allowed; most recently losing to Iowa 19-20 on September 26, 2026.
These teams have met once in our results history, on October 25, 2025: Michigan State 20, Michigan 31.
Injury report: Michigan State lists 7 (Cam Fancher, Injured; Cam Edwards, Injured; Jay Coyne, Injured; more below); Michigan lists 5 (Jonathan Brown, Injured; Micah Ka'apana, Injured; Braydon Alford, Injured; more below).
Injuries
Michigan State
- Cam Fancher: Injured, Knee
- Cam Edwards: Injured, Knee
- Jay Coyne: Injured, Undisclosed
- Joe Caudill: Injured, Undisclosed
- Caleb Wheatland: Injured, Undisclosed
- NiJhay Burt: Injured, Knee
- Devin Vaught: Injured, Knee
Michigan
- Jonathan Brown: Injured, Undisclosed
- Micah Ka'apana: Injured, Undisclosed
- Braydon Alford: Injured, Undisclosed
- Mason Curtis: Injured, Undisclosed
- Jordan Deck: Injured, Undisclosed
Recent form
Michigan State
- September 26, 2026: L 13-31 vs Nebraska
- September 19, 2026: L 10-27 at Notre Dame
- September 12, 2026: W 35-7 vs Eastern Michigan
- September 4, 2026: W 30-20 vs Toledo
- November 29, 2025: W 38-28 vs Maryland
Michigan
- September 26, 2026: L 19-20 vs Iowa
- September 19, 2026: W 52-17 vs UTEP
- September 12, 2026: W 17-10 vs Oklahoma
- September 5, 2026: W 13-12 vs Western Michigan
- December 31, 2025: L 27-41 at Texas
Head to head
- October 25, 2025: Michigan State 20, Michigan 31