LSU vs Kentucky Prediction, Picks & Odds (Week 6)

Sat, Oct 10, 7:00 PM ET

Market favorite

LSU moneyline -455, published Oct 3, 2026, 12:28 PM ET.

About this pick

LSU is the market favorite on the moneyline at -455 when the pick was published on Oct 3. Until our ratings model is live, each pick is the market favorite, and that price implies a 82% chance of LSU winning.

This season, LSU is 3-1 with 155 points for and 62 against; Kentucky is 3-1 with 138 points for and 100 against.

LSU is 3-2 in its last 5, averaging 38.0 scored and 20.0 allowed; most recently beating Texas A&M 35-6 on September 26, 2026. Kentucky is 3-2 in its last 5, averaging 27.6 scored and 28.2 allowed; most recently beating South Alabama 45-21 on September 26, 2026.

Injury report: LSU lists 4 (Phillip Wright III, Injured; Trey'Dez Green, Injured; Jaiden Braker, Injured; more below); Kentucky lists 4 (Tovani Mizell, Injured; DJ Miller, Injured; Jamarrion Harkless, Injured; more below).

LSU vs Kentucky odds

American odds, main line. The best price in each column is in bold.

Sportsbook	LSU ML	Kentucky ML	LSU spread	Kentucky spread	Over	Under
BetOnline	—	—	-10 -115	+10 -105	O 55 -110	U 55 -110

Injuries

LSU

Phillip Wright III: Injured, Undisclosed
Trey'Dez Green: Injured, Leg
Jaiden Braker: Injured, Undisclosed
Whit Weeks: Injured, Leg

Kentucky

Tovani Mizell: Injured, Undisclosed
DJ Miller: Injured, Leg
Jamarrion Harkless: Injured, Leg
Nasir Addison: Injured, Undisclosed

Recent form

LSU

September 26, 2026: W 35-6 vs Texas A&M
September 19, 2026: L 24-32 at Ole Miss
September 12, 2026: W 45-14 vs Louisiana Tech
September 5, 2026: W 51-10 vs Clemson
December 27, 2025: L 35-38 at Houston

Kentucky

September 26, 2026: W 45-21 vs South Alabama
September 19, 2026: W 31-21 at Texas A&M
September 12, 2026: L 17-45 vs Alabama
September 5, 2026: W 45-13 vs Youngstown State
November 29, 2025: L 0-41 at Louisville

More on this game

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