Buffalo vs Toledo Prediction, Picks & Odds (Week 6)
Sat, Oct 10, 3:30 PM ET
Why we pick this side
This season, Buffalo is 2-2 with 85 points for and 133 against; Toledo is 3-1 with 173 points for and 104 against.
Buffalo is 2-3 in its last 5, averaging 22.2 scored and 32.8 allowed; most recently beating Robert Morris 31-28 on September 26, 2026. Toledo is 3-2 in its last 5, averaging 39.0 scored and 26.2 allowed; most recently beating San Diego State 41-16 on September 26, 2026.
Injury report: Buffalo lists 8 (Elijah Holmes, Injured; Terrance Shelton Jr., Injured; Jasaiah Gathings, Injured; more below); Toledo lists 7 (Dane Nauman, Injured; Corey Smith, Injured; Trenton Jones, Injured; more below).
Injuries
Buffalo
- Elijah Holmes: Injured, Knee
- Terrance Shelton Jr.: Injured, Arm
- Jasaiah Gathings: Injured, Undisclosed
- Bobby Mays: Injured, Undisclosed
- Caleb Oliver: Injured, Knee
- Joey Cheshire: Injured, Undisclosed
- Na'Rod Jarvis: Injured, Arm
- Ramari Taylor: Injured, Undisclosed
Toledo
- Dane Nauman: Injured, Undisclosed
- Corey Smith: Injured, Undisclosed
- Trenton Jones: Injured, Undisclosed
- Ezra Odinjor: Injured, Undisclosed
- LaDavion Osborn: Injured, Undisclosed
- Ziiyahn Blair: Injured, Undisclosed
- Ziiyahn Blair: Injured, Undisclosed
Recent form
Buffalo
- September 26, 2026: W 31-28 vs Robert Morris
- September 19, 2026: L 13-55 at Penn State
- September 12, 2026: L 20-33 at Florida International
- September 3, 2026: W 21-17 vs UAlbany
- November 28, 2025: L 26-31 vs Ohio
Toledo
- September 26, 2026: W 41-16 vs San Diego State
- September 19, 2026: W 49-48 vs Temple
- September 12, 2026: W 63-10 vs Central Connecticut
- September 4, 2026: L 20-30 at Michigan State
- December 23, 2025: L 22-27 at Louisville