Lions at Panthers Pick, Odds & Prediction – NFL Week 4

Lions at Panthers

Sun, Oct 4, 8:20 PM ET · Status: Final · Bank of America Stadium, Charlotte

Final: Lions 26, Panthers 32

Our pick and the result

No pick

Line moves

No line moves yet. A move shows here once at least two sportsbooks agree on a new spread or total.

Matchup

Recent results

Lions

• W 31-24 vs New York Jets, September 27
• L 31-41 at Buffalo Bills, September 17
• W 31-30 vs New Orleans Saints, September 13
• W 19-16 at Chicago Bears, January 4 (2025 season)
• L 10-23 at Minnesota Vikings, December 25 (2025 season)

Panthers

• L 18-21 at Cleveland Browns, September 27
• W 34-3 at Atlanta Falcons, September 20
• L 37-59 vs Chicago Bears, September 13
• L 31-34 vs Los Angeles Rams, January 10 (2025 playoffs)
• L 14-16 at Tampa Bay Buccaneers, January 3 (2025 season)

Head to head

• October 8, 2023: Carolina Panthers 24, Detroit Lions 42

Match preview

The Panthers won 32-26.

In 3 games this season, the Lions have scored 31.0 points a game and allowed 31.7. On September 27, the Lions beat the New York Jets 31-24. The Panthers have averaged 29.7 points scored and 27.7 allowed in 3 games this season. Last time out, the Panthers lost to the Cleveland Browns 21-18.

Next NFL games

• Pittsburgh Steelers at New Orleans Saints, Oct 25, 9:30 AM ET. Pick: Pittsburgh Steelers, posted at -141 · Bet Pittsburgh Steelers -167 at BetOnline →
• San Francisco 49ers at Atlanta Falcons, Oct 25, 1:00 PM ET. Pick: San Francisco 49ers, posted at -233 · Bet San Francisco 49ers -145 at BetUS →
• Cleveland Browns at Tennessee Titans, Oct 25, 1:00 PM ET. Pick: Cleveland Browns, posted at -127 · Bet Cleveland Browns -128 at BetOnline →
• Indianapolis Colts at Minnesota Vikings, Oct 25, 1:00 PM ET. Pick: Minnesota Vikings, posted at -238 · Bet Minnesota Vikings -278 at BetOnline →

Other NFL Week 4 games

• Steelers at Browns, Oct 1, 8:15 PM ET
• Colts at Commanders, Oct 4, 9:30 AM ET
• Cardinals at Giants, Oct 4, 1:00 PM ET
• Titans at Ravens, Oct 4, 1:00 PM ET
• Patriots at Bills, Oct 4, 1:00 PM ET
• Cowboys at Texans, Oct 4, 1:00 PM ET
• Packers at Buccaneers, Oct 4, 1:00 PM ET
• Jets at Bears, Oct 4, 1:00 PM ET
• Rams at Eagles, Oct 4, 1:00 PM ET
• Jaguars at Bengals, Oct 4, 1:00 PM ET
• Dolphins at Vikings, Oct 4, 4:05 PM ET
• Broncos at 49ers, Oct 4, 4:25 PM ET
• Chiefs at Raiders, Oct 4, 4:25 PM ET
• Chargers at Seahawks, Oct 4, 4:25 PM ET
• Falcons at Saints, Oct 5, 8:15 PM ET

All NFL picks · NFL odds

Lions vs Panthers FAQ

Who is favored in Lions vs Panthers?

The game is over: Lions 26, Panthers 32.

What is the spread for Lions vs Panthers?

The spread closed when the game started.

What is the over/under for Lions vs Panthers?

The over/under closed when the game started.

When and where is Lions vs Panthers?

The Lions play the Panthers on Sunday, October 4 at 8:20 PM ET at Bank of America Stadium, Charlotte.