Broncos at 49ers Pick, Odds & Prediction – NFL Week 4

Broncos at 49ers

Sun, Oct 4, 4:25 PM ET · Status: Final · Levi's Stadium, Santa Clara

Final: Broncos 14, 49ers 24

Our pick and the result

No pick

Line moves

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Matchup

Recent results

Broncos

• W 30-26 vs Los Angeles Rams, September 27
• W 20-13 vs Jacksonville Jaguars, September 20
• L 10-31 at Kansas City Chiefs, September 14
• L 7-10 vs New England Patriots, January 25 (2025 playoffs)
• W 33-30 vs Buffalo Bills, January 17 (2025 playoffs)

49ers

• W 36-30 vs Arizona Cardinals, September 27
• W 35-13 vs Miami Dolphins, September 20
• W 27-7 at Los Angeles Rams, September 10
• L 6-41 at Seattle Seahawks, January 17 (2025 playoffs)
• W 23-19 at Philadelphia Eagles, January 11 (2025 playoffs)

Match preview

The 49ers won 24-14.

This season the Broncos score 20.0 points a game and allow 23.3. Latest game for the Broncos: a 30-26 win over the Los Angeles Rams. This season the 49ers score 32.7 points a game and allow 16.7. On September 27, the 49ers beat the Arizona Cardinals 36-30.

Next NFL games

• Pittsburgh Steelers at New Orleans Saints, Oct 25, 9:30 AM ET. Pick: Pittsburgh Steelers, posted at -141 · Bet Pittsburgh Steelers -167 at BetOnline →
• San Francisco 49ers at Atlanta Falcons, Oct 25, 1:00 PM ET. Pick: San Francisco 49ers, posted at -233 · Bet San Francisco 49ers -145 at BetUS →
• Cleveland Browns at Tennessee Titans, Oct 25, 1:00 PM ET. Pick: Cleveland Browns, posted at -127 · Bet Cleveland Browns -128 at BetOnline →
• Indianapolis Colts at Minnesota Vikings, Oct 25, 1:00 PM ET. Pick: Minnesota Vikings, posted at -238 · Bet Minnesota Vikings -278 at BetOnline →

Other NFL Week 4 games

• Steelers at Browns, Oct 1, 8:15 PM ET
• Colts at Commanders, Oct 4, 9:30 AM ET
• Cardinals at Giants, Oct 4, 1:00 PM ET
• Titans at Ravens, Oct 4, 1:00 PM ET
• Patriots at Bills, Oct 4, 1:00 PM ET
• Cowboys at Texans, Oct 4, 1:00 PM ET
• Packers at Buccaneers, Oct 4, 1:00 PM ET
• Jets at Bears, Oct 4, 1:00 PM ET
• Rams at Eagles, Oct 4, 1:00 PM ET
• Jaguars at Bengals, Oct 4, 1:00 PM ET
• Dolphins at Vikings, Oct 4, 4:05 PM ET
• Chiefs at Raiders, Oct 4, 4:25 PM ET
• Chargers at Seahawks, Oct 4, 4:25 PM ET
• Lions at Panthers, Oct 4, 8:20 PM ET
• Falcons at Saints, Oct 5, 8:15 PM ET

All NFL picks · NFL odds

Broncos vs 49ers FAQ

Who is favored in Broncos vs 49ers?

The game is over: Broncos 14, 49ers 24.

What is the spread for Broncos vs 49ers?

The spread closed when the game started.

What is the over/under for Broncos vs 49ers?

The over/under closed when the game started.

When and where is Broncos vs 49ers?

The Broncos play the 49ers on Sunday, October 4 at 4:25 PM ET at Levi's Stadium, Santa Clara.