Southern Miss vs Troy Prediction, Picks & Odds (Week 6)
Tue, Oct 6, 8:00 PM ET
Market favorite
Troy moneyline -385, published Oct 3, 2026, 12:28 PM ET.
About this pick
Troy is the market favorite on the moneyline at -385 when the pick was published on Oct 3. Until our ratings model is live, each pick is the market favorite, and that price implies a 79% chance of Troy winning.
This season, Southern Miss is 1-3 with 98 points for and 118 against; Troy is 2-2 with 85 points for and 86 against.
Southern Miss is 1-4 in its last 5, averaging 22.8 scored and 29.0 allowed; most recently losing to Tulane 21-24 on September 26, 2026. Troy is 2-3 in its last 5, averaging 19.6 scored and 20.6 allowed; most recently losing to Utah State 10-21 on September 26, 2026.
These teams have met once in our results history, on November 29, 2025: Troy 28, Southern Miss 18.
Injury report: Southern Miss lists 8 (Ethan Hampton, Injured; Robert Briggs, Injured; Jaylen Himes, Injured; more below); Troy lists 3 (Fabian Rogosch, Injured; Jackson Worley, Injured; Will Norman, Injured).
Injuries
Southern Miss
- Ethan Hampton: Injured, Hand
- Robert Briggs: Injured, Undisclosed
- Jaylen Himes: Injured, Foot
- Grant Page: Injured, Elbow
- Nasim Cairo: Injured, Hand
- Jameer Lewis: Injured, Foot
- Mathis Haygood: Injured, Elbow
- Tyler Lassiter: Injured, Undisclosed
Troy
- Fabian Rogosch: Injured, Leg
- Jackson Worley: Injured, Undisclosed
- Will Norman: Injured, Undisclosed
Recent form
Southern Miss
- September 26, 2026: L 21-24 at Tulane
- September 19, 2026: L 20-48 vs UConn
- September 12, 2026: L 8-43 at Auburn
- September 5, 2026: W 49-3 vs Alcorn State
- December 23, 2025: L 16-27 vs Western Kentucky
Troy
- September 26, 2026: L 10-21 at Utah State
- September 19, 2026: L 17-27 at Missouri
- September 12, 2026: W 34-17 vs Alabama State
- September 5, 2026: W 24-21 vs Sam Houston
- December 16, 2025: L 13-17 at Jacksonville State
Head to head
- November 29, 2025: Troy 28, Southern Miss 18